Vol 6, No 7 (2015) > Chemical Engineering >

Selected Natural Deep Eutectic Solvents for the Extraction of α-Mangostin from Mangosteen (Garcinia mangostana L.) Pericarp

Kamarza Mulia, Elsa Krisanti, Felita Terahadi, Sylvania Putri


Abstract: This research considers the application of Natural Deep Eutectic Solvents
(NADES) as green solvents for the extraction of bioactive compounds, mainly α-mangostin,
from the pericarp of mangosteen (Garcinia
L.). Extractions were carried out using NADES consisting of choline chloride, a
quarternary ammonium salt, and four hydrogen bond donors: 1,2-propanediol,
citric acid, glycerol, and glucose. The highest α-mangostin extraction yield of
2.6 %
(w/w) in dried pericarp was obtained using a mixture of choline chloride and
1,2-propanediol in 1:3 mole ratio. The presence of hydrogen bonding was
indicated by the broadening of the OH peak in the infra-red spectra of the NADES used. The polarity and viscosity data of NADES were determined to describe the
solubility of a-mangostin. The decomposition
and glass transition temperatures were determined in order to study their
thermal behavior and stability. The results of this study suggest that NADES
made of choline chloride and diol-based hydrogen bond donors are
effective for the extraction of bioactive compounds from the mangosteen
Keywords: α-mangostin; Deep eutectic solvent; Extraction; Garcinia mangostana L.; NADES

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